Notice as Spider-Man uses both his red and blue/black suits, his alignment meter
will progress toward his good or bad side respectively. Take a look at the photo
in the lower left-hand corner of the screen as well as the alignment meter in the
pause menu. While the alignment picture is displaying the red and blue suit, only
superheroes will aid him, and conversely while the black symbiote is displayed, 
only villains will help. As long as the picture is one color, it does not matter
what suit you use until the meter color crosses the middle. If you maintain a very
close middle ground, you can effectively utilize both the superheroes and villains
(although not at the same time.) Strategize by getting both red and black points 
until your alignment meter is precisely in the middle. You might notice as you 
defeat one enemy using a suit that Spidey's picture will change in the lower left
hand corner of the screen. Even if you have a hero summoned, if you quickly switch
to the black suit and defeat more of the enemies until the photo changes, that hero
will still stay with you until you dismiss him or your special meter runs out. The 
same holds true for villains and switching back to the red suit. The alignment 
affects whom you can summon, not who you have already called in. Use this strategy
to defeat your enemies, get the most experience points, and unlock all the moves.