Use the following trick to collect 4,300 Red Orbs in about twenty seconds. 
At the start of
the mission, destroy the rocks to the left of you. Proceed into the tunnel 
and also destroy the
rocks that are there. You will see the big red crystal near the Secret 
Mission. In order to get
the most orbs, start with the Stinger then immediately go into Devil Trigger 
mode and quickly
mash away. Once done, press Start, go to "Systems" then "Retry Mission".
This is the easiest way to get a lot of Red Orbs in a short amount of time.