Use the following weapons to defeat the corresponding opponent:
Galaxy Man: Use the Mega Buster. 
Jewel Man: Use the Black Hole Bomb. 
Plug Man: Use the Jewel Satellite. 
Tornado Man: Use the Plug Ball. 
Magma Man: Use the Tornado Blow. 
Hornet Man: Use the Magma Bazooka. 
Splash Woman: Use the Hornet Chaser. 
Concrete Man: Use the Laser Trident. 
Wall Shooters: Use the Mega Buster. 
Giant Machine: Use the Laser Trident. 
Blob Monster: Use the Black Hole Bomb. 
Dr. Wily, Part 1: Use the Mega Buster. 
Dr. Wily, Part 2: Use the Mega Buster. 
Dr. Wily, Part 3: Use the Plug Ball.